The first workshop of the Thematic Einstein Semester will be held from November 1 to 3 at the Zuse Institute Berlin. It is an opportunity to find future research topics and collaborations. It is the prelude to a Thematic Einstein Semester, which deals with the interaction of mathematics and non-mathematical disciplines. In our first workshop we deal with research questions and data from different disciplines and see how mathematics comes into play in interdisciplinary projects. Success stories but also critical views on this collaboration have their say. The following questions are examined in particular: Transition from the research question to the mathematical problem – is that possible? Can expert knowledge (beyond the concrete data) be represented mathematically? What is the impact of complexity reduction? Can mathematical structures be found in interdisciplinary research objects?